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Antibody-dependent enhancement of severe dengue disease in humans
For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to enhance viral replication in vitro and severe disease in animal models. Although suspected, such antibody-dependent enhancement of severe disease has not been shown to occur in humans. Using multiple statistica...
Autores principales: | Katzelnick, Leah C., Gresh, Lionel, Halloran, M. Elizabeth, Mercado, Juan Carlos, Kuan, Guillermina, Gordon, Aubree, Balmaseda, Angel, Harris, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858873/ https://www.ncbi.nlm.nih.gov/pubmed/29097492 http://dx.doi.org/10.1126/science.aan6836 |
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