Quantifying autophagy using novel LC3B and p62 TR-FRET assays

Autophagy is a cellular mechanism that can generate energy for cells or clear misfolded or aggregated proteins, and upregulating this process has been proposed as a therapeutic approach for neurodegenerative diseases. Here we describe a novel set of LC3B-II and p62 time-resolved fluorescence resonan...

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Detalles Bibliográficos
Autores principales: Bresciani, Alberto, Spiezia, Maria Carolina, Boggio, Roberto, Cariulo, Cristina, Nordheim, Anja, Altobelli, Roberta, Kuhlbrodt, Kirsten, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Wityak, John, Fodale, Valentina, Marchionini, Deanna M., Weiss, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858923/
https://www.ncbi.nlm.nih.gov/pubmed/29554128
http://dx.doi.org/10.1371/journal.pone.0194423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858923/
https://www.ncbi.nlm.nih.gov/pubmed/29554128
http://dx.doi.org/10.1371/journal.pone.0194423

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