High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer

Human Tousled-like kinases (TLKs) are highly conserved serine/threonine protein kinases responsible for cell proliferation, DNA repair, and genome surveillance. Their possible involvement in cancer via efficient DNA repair mechanisms have made them clinically relevant molecular targets for anticance...

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Detalles Bibliográficos
Autores principales: Bhoir, Siddhant, Shaik, Althaf, Thiruvenkatam, Vijay, Kirubakaran, Sivapriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859067/
https://www.ncbi.nlm.nih.gov/pubmed/29555908
http://dx.doi.org/10.1038/s41598-018-22744-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859067/
https://www.ncbi.nlm.nih.gov/pubmed/29555908
http://dx.doi.org/10.1038/s41598-018-22744-5

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