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Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9
S100A8 and S100A9 are members of the S100 family of cytoplasmic EF-hand Ca(2+)-binding proteins and are abundantly expressed in the cytosol of neutrophils. In addition to their intracellular roles, S100A8/A9 can be secreted in the extracellular environment and are considered as alarmins able to ampl...
Autores principales: | Schenten, Véronique, Plançon, Sébastien, Jung, Nicolas, Hann, Justine, Bueb, Jean-Luc, Bréchard, Sabrina, Tschirhart, Eric J., Tolle, Fabrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859079/ https://www.ncbi.nlm.nih.gov/pubmed/29593718 http://dx.doi.org/10.3389/fimmu.2018.00447 |
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