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Altered DNA methylation associated with a translocation linked to major mental illness
Recent work has highlighted a possible role for altered epigenetic modifications, including differential DNA methylation, in susceptibility to psychiatric illness. Here, we investigate blood-based DNA methylation in a large family where a balanced translocation between chromosomes 1 and 11 shows gen...
Autores principales: | McCartney, Daniel L., Walker, Rosie M., Morris, Stewart W., Anderson, Susan M., Duff, Barbara J., Marioni, Riccardo E., Millar, J. Kirsty, McCarthy, Shane E., Ryan, Niamh M., Lawrie, Stephen M., Watson, Andrew R., Blackwood, Douglas H. R., Thomson, Pippa A., McIntosh, Andrew M., McCombie, W. Richard, Porteous, David J., Evans, Kathryn L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859082/ https://www.ncbi.nlm.nih.gov/pubmed/29555928 http://dx.doi.org/10.1038/s41537-018-0047-7 |
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