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Functional Polarity of Microvascular Brain Endothelial Cells Supported by Neurovascular Unit Computational Model of Large Neutral Amino Acid Homeostasis
The homeostatic regulation of large neutral amino acid (LNAA) concentration in the brain interstitial fluid (ISF) is essential for proper brain function. LNAA passage into the brain is primarily mediated by the complex and dynamic interactions between various solute carrier (SLC) transporters expres...
Autores principales: | Taslimifar, Mehdi, Buoso, Stefano, Verrey, Francois, Kurtcuoglu, Vartan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859092/ https://www.ncbi.nlm.nih.gov/pubmed/29593549 http://dx.doi.org/10.3389/fphys.2018.00171 |
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