Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function

BACKGROUND: Inhibition of the nuclear factor kappa beta (NF-κβ) pathway has been proposed as a therapeutic target due to its key role in the expression of pro-inflammatory genes, including pro-inflammatory cytokines, chemokines, and adhesion molecules. Caffeic acid phenethyl ester (CAPE) is a natura...

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Detalles Bibliográficos
Autores principales: Khan, Mohammed N., Lane, Majella E., McCarron, Paul A., Tambuwala, Murtaza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859149/
https://www.ncbi.nlm.nih.gov/pubmed/28528363
http://dx.doi.org/10.1007/s10787-017-0364-x

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