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Alarmin HMGB1 induces systemic and brain inflammatory exacerbation in post-stroke infection rat model

Post-stroke infection (PSI) is known to worsen functional outcomes of stroke patients and accounts to one-third of stroke-related deaths in hospital. In our previous reports, we demonstrated that massive release of high-mobility group box protein 1 (HMGB1), an endogenous danger signal molecule, is p...

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Detalles Bibliográficos
Autores principales: Kim, Il-Doo, Lee, Hahnbie, Kim, Seung-Woo, Lee, Hye-Kyung, Choi, Juli, Han, Pyung-Lim, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859283/
https://www.ncbi.nlm.nih.gov/pubmed/29555931
http://dx.doi.org/10.1038/s41419-018-0438-8