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Alarmin HMGB1 induces systemic and brain inflammatory exacerbation in post-stroke infection rat model
Post-stroke infection (PSI) is known to worsen functional outcomes of stroke patients and accounts to one-third of stroke-related deaths in hospital. In our previous reports, we demonstrated that massive release of high-mobility group box protein 1 (HMGB1), an endogenous danger signal molecule, is p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859283/ https://www.ncbi.nlm.nih.gov/pubmed/29555931 http://dx.doi.org/10.1038/s41419-018-0438-8 |