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Fascin is secreted in male's serum: results of a pilot study

AIM: Fascin is a 55 kDa globular protein with an important role in cell migration. Aim of study was to investigate serum fascin in healthy males. MATERIALS & METHODS: From 1 July 2016 to 31 December 2016, we collected serum from 46 males. Serum fascin level was performed using ELISA kit from USB...

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Detalles Bibliográficos
Autores principales: Porav-Hodade, Daniel, Martha, Orsolya, Balan, Daniel, Tataru, Sabin, Hutanu, Adina, Sin, Anca, Vartolomei, Mihai Dorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859328/
https://www.ncbi.nlm.nih.gov/pubmed/29568562
http://dx.doi.org/10.4155/fsoa-2017-0098
Descripción
Sumario:AIM: Fascin is a 55 kDa globular protein with an important role in cell migration. Aim of study was to investigate serum fascin in healthy males. MATERIALS & METHODS: From 1 July 2016 to 31 December 2016, we collected serum from 46 males. Serum fascin level was performed using ELISA kit from USBiological (Salem, MA, USA). RESULTS: Median age was 64 years. Mean fascin serum level was 9.84 ng/ml, mean prostate-specific antigen (PSA) was 2.74 ng/ml and mean prostate volume was 37.64 cc. The 51–60 years group had a mean of 10.53 ng/ml, the 61–70 group a mean of 9.7 ng/ml and the 71–80 group had a mean of 9.41 ng/ml fascin serum level. CONCLUSION: Fascin serum level did not differ according to age in males.