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14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once
In this review we highlight the advances achieved in the investigation of the role of 14-3-3 proteins in hormone signaling, biosynthesis, and transport. 14-3-3 proteins are a family of conserved molecules that target a number of protein clients through their ability to recognize well-defined phospho...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859350/ https://www.ncbi.nlm.nih.gov/pubmed/29593761 http://dx.doi.org/10.3389/fpls.2018.00297 |
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author | Camoni, Lorenzo Visconti, Sabina Aducci, Patrizia Marra, Mauro |
author_facet | Camoni, Lorenzo Visconti, Sabina Aducci, Patrizia Marra, Mauro |
author_sort | Camoni, Lorenzo |
collection | PubMed |
description | In this review we highlight the advances achieved in the investigation of the role of 14-3-3 proteins in hormone signaling, biosynthesis, and transport. 14-3-3 proteins are a family of conserved molecules that target a number of protein clients through their ability to recognize well-defined phosphorylated motifs. As a result, they regulate several cellular processes, ranging from metabolism to transport, growth, development, and stress response. High-throughput proteomic data and two-hybrid screen demonstrate that 14-3-3 proteins physically interact with many protein clients involved in the biosynthesis or signaling pathways of the main plant hormones, while increasing functional evidence indicates that 14-3-3-target interactions play pivotal regulatory roles. These advances provide a framework of our understanding of plant hormone action, suggesting that 14-3-3 proteins act as hubs of a cellular web encompassing different signaling pathways, transducing and integrating diverse hormone signals in the regulation of physiological processes. |
format | Online Article Text |
id | pubmed-5859350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58593502018-03-28 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once Camoni, Lorenzo Visconti, Sabina Aducci, Patrizia Marra, Mauro Front Plant Sci Plant Science In this review we highlight the advances achieved in the investigation of the role of 14-3-3 proteins in hormone signaling, biosynthesis, and transport. 14-3-3 proteins are a family of conserved molecules that target a number of protein clients through their ability to recognize well-defined phosphorylated motifs. As a result, they regulate several cellular processes, ranging from metabolism to transport, growth, development, and stress response. High-throughput proteomic data and two-hybrid screen demonstrate that 14-3-3 proteins physically interact with many protein clients involved in the biosynthesis or signaling pathways of the main plant hormones, while increasing functional evidence indicates that 14-3-3-target interactions play pivotal regulatory roles. These advances provide a framework of our understanding of plant hormone action, suggesting that 14-3-3 proteins act as hubs of a cellular web encompassing different signaling pathways, transducing and integrating diverse hormone signals in the regulation of physiological processes. Frontiers Media S.A. 2018-03-13 /pmc/articles/PMC5859350/ /pubmed/29593761 http://dx.doi.org/10.3389/fpls.2018.00297 Text en Copyright © 2018 Camoni, Visconti, Aducci and Marra. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Camoni, Lorenzo Visconti, Sabina Aducci, Patrizia Marra, Mauro 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title | 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title_full | 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title_fullStr | 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title_full_unstemmed | 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title_short | 14-3-3 Proteins in Plant Hormone Signaling: Doing Several Things at Once |
title_sort | 14-3-3 proteins in plant hormone signaling: doing several things at once |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859350/ https://www.ncbi.nlm.nih.gov/pubmed/29593761 http://dx.doi.org/10.3389/fpls.2018.00297 |
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