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Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci

CCCTC-binding factor (CTCF) is largely responsible for the 3D architecture of the genome, in concert with the action of cohesin, through the creation of long-range chromatin loops. Cohesin is hypothesized to be the main driver of these long-range chromatin interactions by the process of loop extrusi...

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Detalles Bibliográficos
Autores principales:	Loguercio, Salvatore, Barajas-Mora, E. Mauricio, Shih, Han-Yu, Krangel, Michael S., Feeney, Ann J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859386/ https://www.ncbi.nlm.nih.gov/pubmed/29593713 http://dx.doi.org/10.3389/fimmu.2018.00425

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