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Methotrexate inhibits effects of platelet-derived growth factor and interleukin-1β on rheumatoid arthritis fibroblast-like synoviocytes

BACKGROUND: A key feature of joints in rheumatoid arthritis (RA) is the formation of hyperplastic destructive pannus tissue, which is orchestrated by activated fibroblast-like synoviocytes (FLS). We have demonstrated that the RA risk gene and tumor suppressor Limb bud and heart development (LBH) reg...

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Detalles Bibliográficos
Autores principales:	Bergström, Beatrice, Carlsten, Hans, Ekwall, Anna-Karin Hultgård
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859417/ https://www.ncbi.nlm.nih.gov/pubmed/29554943 http://dx.doi.org/10.1186/s13075-018-1554-7

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