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Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2

BACKGROUND: Cerebral hypoperfusion is a pivotal risk factor for vascular dementia (VD), for which effective therapy remains inadequate. Persistent inflammatory responses and excessive chemotaxis of microglia/macrophages in the brain may accelerate the progression of VD. Endocannabinoids are involved...

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Detalles Bibliográficos
Autores principales:	Luo, Xian-Qin, Li, Ao, Yang, Xue, Xiao, Xiao, Hu, Rong, Wang, Tian-Wen, Dou, Xiao-Yun, Yang, Da-Jian, Dong, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859430/ https://www.ncbi.nlm.nih.gov/pubmed/29560022 http://dx.doi.org/10.1186/s13020-018-0173-1

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