Cargando…
OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway
BACKGROUND: The aim of this study was to investigate the mechanisms of OX40L in regulating helper T (Th) cells differentiation through phosphoinositide 3-kinase (PI3K)/AKT and p38 mitogen-activated protein kinase signaling pathway in vitro and in vivo experiments. METHODS: Serum samples of patients...
Autores principales: | Huang, Li, Wang, Meijuan, Yan, Yongdong, Gu, Wenjing, Zhang, Xinxing, Tan, Jiahong, Sun, Huiming, Ji, Wei, Chen, Zhengrong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859438/ https://www.ncbi.nlm.nih.gov/pubmed/29554934 http://dx.doi.org/10.1186/s12967-018-1436-4 |
Ejemplares similares
-
OX40/OX40 Ligand Interactions in T-Cell Regulation and Asthma
por: Kaur, Davinder, et al.
Publicado: (2012) -
The OX40/OX40L Axis Regulates T Follicular Helper Cell Differentiation: Implications for Autoimmune Diseases
por: Fu, NanNan, et al.
Publicado: (2021) -
The role of inducible costimulatory molecular ligand (ICOSL) in children with neutrophilic asthma
por: Dong, Heting, et al.
Publicado: (2020) -
E3 Ubiquitin Ligase March1 Facilitates OX40L Expression in Allergen-Stimulated Dendritic Cells Through Mediating the Ubiquitination of HDAC11
por: Zhang, Xinxing, et al.
Publicado: (2021) -
B7-H3 participates in the development of Asthma by augmentation of the inflammatory response independent of TLR2 pathway
por: Gu, Wenjing, et al.
Publicado: (2017)