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Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy

When pathogenic stresses are recognized by innate immune cells, inflammasomes are assembled and caspase-1 is activated, resulting in the conversion of pro-IL-18 into mature IL-18. Because natural killer (NK) cells express IL-18 receptors, IL-18 may play roles in immune functions of NK cells. In the...

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Detalles Bibliográficos
Autores principales:	Senju, Hiroaki, Kumagai, Asuka, Nakamura, Yoichi, Yamaguchi, Hiroyuki, Nakatomi, Katsumi, Fukami, Shota, Shiraishi, Kengo, Harada, Yuka, Nakamura, Mitsuhiro, Okamura, Haruki, Tanaka, Yoshimasa, Mukae, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859478/ https://www.ncbi.nlm.nih.gov/pubmed/29559850 http://dx.doi.org/10.7150/ijbs.22809

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