Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy

Diabetic retinopathy (DR) is a well-known risk factor in the development of radiation maculopathy (RM). Steroids have been shown to improve the vision and reduce the macular thickness in patients with RM. This observational case report highlights altered course of DR after a course of radiotherapy f...

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Detalles Bibliográficos
Autores principales: Verma, Aditya, Khetan, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859617/
https://www.ncbi.nlm.nih.gov/pubmed/29480273
http://dx.doi.org/10.4103/ijo.IJO_782_17
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author Verma, Aditya
Khetan, Vikas
author_facet Verma, Aditya
Khetan, Vikas
author_sort Verma, Aditya
collection PubMed
description Diabetic retinopathy (DR) is a well-known risk factor in the development of radiation maculopathy (RM). Steroids have been shown to improve the vision and reduce the macular thickness in patients with RM. This observational case report highlights altered course of DR after a course of radiotherapy for orbital lymphoma, after a single dose of intravitreal dexamethasone implant showed a dramatic revascularization of the ischemic macula, with a significant reduction in the size of ischemic area. This appears to be the first case in literature corroborating the favorable effect on steroids on retinal vasculature, seen angiographically.
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spelling pubmed-58596172018-03-23 Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy Verma, Aditya Khetan, Vikas Indian J Ophthalmol Case Report Diabetic retinopathy (DR) is a well-known risk factor in the development of radiation maculopathy (RM). Steroids have been shown to improve the vision and reduce the macular thickness in patients with RM. This observational case report highlights altered course of DR after a course of radiotherapy for orbital lymphoma, after a single dose of intravitreal dexamethasone implant showed a dramatic revascularization of the ischemic macula, with a significant reduction in the size of ischemic area. This appears to be the first case in literature corroborating the favorable effect on steroids on retinal vasculature, seen angiographically. Medknow Publications & Media Pvt Ltd 2018-03 /pmc/articles/PMC5859617/ /pubmed/29480273 http://dx.doi.org/10.4103/ijo.IJO_782_17 Text en Copyright: © 2018 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Verma, Aditya
Khetan, Vikas
Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title_full Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title_fullStr Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title_full_unstemmed Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title_short Transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
title_sort transient reversal of macular ischemia with intravitreal steroid implant injection in a case of radiation maculopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859617/
https://www.ncbi.nlm.nih.gov/pubmed/29480273
http://dx.doi.org/10.4103/ijo.IJO_782_17
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AT khetanvikas transientreversalofmacularischemiawithintravitrealsteroidimplantinjectioninacaseofradiationmaculopathy

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