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Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling

BACKGROUND: Articular cartilage degeneration plays a key role in the pathogenesis of osteoarthritis (OA). Bushenhuoxue formula (BSHXF) has been widely used in the treatment of OA in clinics. However, the molecular mechanisms responsible for the chondroprotective effect of BSHXF remain to be elucidat...

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Detalles Bibliográficos
Autores principales: Wang, Ping-er, Zhang, Lei, Ying, Jun, Jin, Xing, Luo, Cheng, Xu, Shibing, Dong, Rui, Xiao, Luwei, Tong, Peijian, Jin, Hongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859632/
https://www.ncbi.nlm.nih.gov/pubmed/29554973
http://dx.doi.org/10.1186/s12967-018-1437-3