Cargando…
Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling
BACKGROUND: Articular cartilage degeneration plays a key role in the pathogenesis of osteoarthritis (OA). Bushenhuoxue formula (BSHXF) has been widely used in the treatment of OA in clinics. However, the molecular mechanisms responsible for the chondroprotective effect of BSHXF remain to be elucidat...
Autores principales: | Wang, Ping-er, Zhang, Lei, Ying, Jun, Jin, Xing, Luo, Cheng, Xu, Shibing, Dong, Rui, Xiao, Luwei, Tong, Peijian, Jin, Hongting |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859632/ https://www.ncbi.nlm.nih.gov/pubmed/29554973 http://dx.doi.org/10.1186/s12967-018-1437-3 |
Ejemplares similares
-
Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
por: Zhang, Lei, et al.
Publicado: (2017) -
Bushenhuoxue Formula Facilitates Articular Cartilage Repair and Attenuates Matrix Degradation by Activation of TGF-β Signaling Pathway
por: Dong, Rui, et al.
Publicado: (2018) -
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
por: Xia, Chenjie, et al.
Publicado: (2023) -
Osteoking Decelerates Cartilage Degeneration in DMM-Induced Osteoarthritic Mice Model Through TGF-β/smad-dependent Manner
por: Ling, Houfu, et al.
Publicado: (2021) -
Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway
por: Aref-Eshghi, Erfan, et al.
Publicado: (2015)