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Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state
BACKGROUND: Obesity is associated with increased risk, poor prognosis and outcome of therapy, in various cancers. Obesity-associated factors or adipokines, especially leptin and resistin, are purported to promote growth, survival, proliferation, and invasiveness of cancer cells. However, the mechani...
Autores principales: | Malvi, Parmanand, Chaube, Balkrishna, Singh, Shivendra Vikram, Mohammad, Naoshad, Vijayakumar, Maleppillil Vavachan, Singh, Snahlata, Chouhan, Surbhi, Bhat, Manoj Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859707/ https://www.ncbi.nlm.nih.gov/pubmed/29568521 http://dx.doi.org/10.1186/s40170-018-0176-5 |
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