Cargando…

Atorvastatin Attenuates Metabolic Remodeling in Ischemic Myocardium through the Downregulation of UCP2 Expression

Uncoupling protein 2 (UCP2) is primarily expressed in the myocardium and is closely related to myocardial ischemia/reperfusion injury and myocardial metabolism. To explore the effects and the mechanisms of UCP2 on atorvastatin-mediated myocardium protection, the rat model of myocardial ischemia was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chunyan, Zhao, Dongming, Liu, Guohui, Zheng, Haikuo, Yang, Hongliang, Yang, Sibao, Yang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859775/ https://www.ncbi.nlm.nih.gov/pubmed/29559841 http://dx.doi.org/10.7150/ijms.22454

Ejemplares similares

Naproxen and Diclofenac Attenuate Atorvastatin-induced Preconditioning of the Myocardium
por: Varga, Zoltan, et al.
Publicado: (2017)

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway
por: Liang, Xing, et al.
Publicado: (2017)

UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling
por: Sancerni, Tiphaine, et al.
Publicado: (2022)

Sympathetic nerve innervation and metabolism in ischemic myocardium in response to remote ischemic perconditioning
por: Kiss, Attila, et al.
Publicado: (2022)

Combination therapy of atorvastatin and probucol on ischemic stroke in clinic
por: Yan, Tao, et al.
Publicado: (2012)

Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue
por: Shore, A., et al.
Publicado: (2010)

Nano-particle engineered atorvastatin delivery to support mesenchymal stem cell survival in infarcted myocardium
por: Yao, Guang-tao, et al.
Publicado: (2018)

Atorvastatin May Attenuate Recurrence of Chronic Subdural Hematoma
por: Liu, Hua, et al.
Publicado: (2016)

Effects of sympathectomy on myocardium remodeling and function
por: Jordão, Maurício Rodrigues, et al.
Publicado: (2021)

Atorvastatin downregulates HSP22 expression in an atherosclerotic model in vitro and in vivo
por: Chen, Qi, et al.
Publicado: (2019)

Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans
por: Zhou, Ming, et al.
Publicado: (2022)

Atorvastatin Improves Ventricular Remodeling after Myocardial Infarction by Interfering with Collagen Metabolism
por: Reichert, Karla, et al.
Publicado: (2016)

UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury
por: Ke, Qingqing, et al.
Publicado: (2020)

A non-invasive nanoparticles for multimodal imaging of ischemic myocardium in rats
por: Chen, Xiajing, et al.
Publicado: (2021)

Correction: Atorvastatin Improves Ventricular Remodeling after Myocardial Infarction by Interfering with Collagen Metabolism
por: Reichert, Karla, et al.
Publicado: (2017)

In vivo label-free optical monitoring of structural and metabolic remodeling of myocardium following infarction
por: Lagarto, João L., et al.
Publicado: (2019)

Extracellular Vesicles Promote Arteriogenesis in Chronically Ischemic Myocardium in the Setting of Metabolic Syndrome
por: Scrimgeour, Laura A., et al.
Publicado: (2019)

Weighted gene co-expression network analysis in identification of key genes and networks for ischemic-reperfusion remodeling myocardium
por: Guo, Nan, et al.
Publicado: (2018)

Engineered Exosomes With Ischemic Myocardium‐Targeting Peptide for Targeted Therapy in Myocardial Infarction
por: Wang, Xu, et al.
Publicado: (2018)

Remodelling of gap junctions and connexin expression in diseased myocardium
por: Severs, Nicholas J., et al.
Publicado: (2008)

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling
por: O'Rourke, Sinead A., et al.
Publicado: (2019)

Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction
por: Tang, Xian-Liang, et al.
Publicado: (2011)

RAGE and Modulation of Ischemic Injury in the Diabetic Myocardium
por: Bucciarelli, Loredana G., et al.
Publicado: (2008)

Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS
por: Wu, Xunxun, et al.
Publicado: (2023)

Correction: A non‑invasive nanoparticles for multimodal imaging of ischemic myocardium in rats
por: Chen, Xiajing, et al.
Publicado: (2022)

Atorvastatin Inhibits Myocardial Cell Apoptosis in a Rat Model with Post-myocardial Infarction Heart Failure by Downregulating ER Stress Response
por: Song, Xian Jing, et al.
Publicado: (2011)

CircUCP2 promotes the tumor progression of non-small cell lung cancer through the miR-149/UCP2 pathway
por: DU, WEI, et al.
Publicado: (2023)

Ramipril attenuates left ventricular remodeling by regulating the expression of activin A-follistatin in a rat model of heart failure
por: Wei, Qun, et al.
Publicado: (2016)

Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium
por: Mishra, Rachana, et al.
Publicado: (2022)

Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke
por: Min, Lianqiu, et al.
Publicado: (2013)

Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing
por: Yang, Qian, et al.
Publicado: (2016)

Postnatal myocardium remodelling generates inhomogeneity in the architecture of the ventricular mass
por: Jouk, Pierre-Simon, et al.
Publicado: (2017)

Correction: Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium
por: Mishra, Rachana, et al.
Publicado: (2023)

Metabolic imaging of in vivo myocardium
por: Springer, Charles S, et al.
Publicado: (2015)

Thermogenic protein UCP1 and UCP3 expression in non-small cell lung cancer: relation with glycolysis and anaerobic metabolism
por: Giatromanolaki, Alexandra, et al.
Publicado: (2017)

The effect of shear on the cytoskeleton remodeling and physiological performance of myocardium cells through Tmod1
por: Zhao, Liang, et al.
Publicado: (2018)

Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats
por: Liu, Qi, et al.
Publicado: (2023)

IRX3 Overexpression Enhances Ucp1 Expression In Vivo
por: Zhang, Zhiyin, et al.
Publicado: (2021)

UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells
por: Li, Yunfeng, et al.
Publicado: (2008)

Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia
por: Nikanorova, Alena A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6s1ddi9oglr7cjvriobunh51at