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A functional SNP upstream of the ADRB2 gene is associated with COPD
BACKGROUND: Previous studies have suggested that β(2)-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. METHODS: In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-tim...
Autores principales: | Li, Jin-Xiu, Fu, Wei-Ping, Zhang, Jing, Zhang, Xiao-Hua, Sun, Chang, Dai, Lu-Ming, Zhong, Li, Yu, Li, Zhang, Ya-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859892/ https://www.ncbi.nlm.nih.gov/pubmed/29588580 http://dx.doi.org/10.2147/COPD.S151153 |
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