Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration

Radiation-induced neuropathic pain is a rare but devastating complication following cancer treatment. It is often progressive, refractory to conservative treatment, and sometimes irreversible. The exact mechanism of radiation-induced neuropathic pain is unknown, but it is associated with perineural...

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Autores principales: Doo, A Ram, Shin, Yu Seob, Yoo, Seonwoo, Park, Jong Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859894/
https://www.ncbi.nlm.nih.gov/pubmed/29588612
http://dx.doi.org/10.2147/JPR.S155070
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author Doo, A Ram
Shin, Yu Seob
Yoo, Seonwoo
Park, Jong Kwan
author_facet Doo, A Ram
Shin, Yu Seob
Yoo, Seonwoo
Park, Jong Kwan
author_sort Doo, A Ram
collection PubMed
description Radiation-induced neuropathic pain is a rare but devastating complication following cancer treatment. It is often progressive, refractory to conservative treatment, and sometimes irreversible. The exact mechanism of radiation-induced neuropathic pain is unknown, but it is associated with perineural fibrosis, atrophy, and ischemia. Systemic administration of local anesthetics is known to be effective for various acute and chronic painful diseases, such as neuropathic pain, as well as inflammatory and nociceptive pains. We report a patient with generalized radiation-induced neuropathic pain successfully treated with systemic lidocaine administration.
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spelling pubmed-58598942018-03-27 Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration Doo, A Ram Shin, Yu Seob Yoo, Seonwoo Park, Jong Kwan J Pain Res Case Report Radiation-induced neuropathic pain is a rare but devastating complication following cancer treatment. It is often progressive, refractory to conservative treatment, and sometimes irreversible. The exact mechanism of radiation-induced neuropathic pain is unknown, but it is associated with perineural fibrosis, atrophy, and ischemia. Systemic administration of local anesthetics is known to be effective for various acute and chronic painful diseases, such as neuropathic pain, as well as inflammatory and nociceptive pains. We report a patient with generalized radiation-induced neuropathic pain successfully treated with systemic lidocaine administration. Dove Medical Press 2018-03-15 /pmc/articles/PMC5859894/ /pubmed/29588612 http://dx.doi.org/10.2147/JPR.S155070 Text en © 2018 Doo et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Doo, A Ram
Shin, Yu Seob
Yoo, Seonwoo
Park, Jong Kwan
Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title_full Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title_fullStr Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title_full_unstemmed Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title_short Radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
title_sort radiation-induced neuropathic pain successfully treated with systemic lidocaine administration
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859894/
https://www.ncbi.nlm.nih.gov/pubmed/29588612
http://dx.doi.org/10.2147/JPR.S155070
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AT parkjongkwan radiationinducedneuropathicpainsuccessfullytreatedwithsystemiclidocaineadministration

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