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Transcription elongation rate affects nascent histone pre-mRNA folding and 3′ end processing
Transcription elongation rate influences cotranscriptional pre-mRNA maturation, but how such kinetic coupling works is poorly understood. The formation of nonadenylated histone mRNA 3′ ends requires recognition of an RNA structure by stem–loop-binding protein (SLBP). We report that slow transcriptio...
Autores principales: | Saldi, Tassa, Fong, Nova, Bentley, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859970/ https://www.ncbi.nlm.nih.gov/pubmed/29483154 http://dx.doi.org/10.1101/gad.310896.117 |
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