Cargando…

Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK

INTRODUCTION: frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood’s frailty index (FI) and Fried’s frailty phenotype (FP). MATERIAL AND METHODS: the pres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Livshits, Gregory, Ni Lochlainn, Mary, Malkin, Ida, Bowyer, Ruth, Verdi, Serena, Steves, Claire J, Williams, Frances M K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860041/ https://www.ncbi.nlm.nih.gov/pubmed/28985290 http://dx.doi.org/10.1093/ageing/afx122

Ejemplares similares

Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study
por: Bowyer, Ruth C. E., et al.
Publicado: (2019)

Multi-OMICS analyses of frailty and chronic widespread musculoskeletal pain suggest involvement of shared neurological pathways
por: Livshits, Gregory, et al.
Publicado: (2018)

Diverging destinies: ‘social’ data within the TwinsUK cohort
por: Bowyer, Ruth C E, et al.
Publicado: (2022)

Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort
por: Louca, Panayiotis, et al.
Publicado: (2020)

OR33-05 Amino Acid Signature of Abdominal Obesity in the TwinsUK Cohort
por: Maltais-Payette, Ina, et al.
Publicado: (2020)

Interplay between the (Poly)phenol Metabolome, Gut Microbiome, and Cardiovascular Health in Women: A Cross-Sectional Study from the TwinsUK Cohort
por: Li, Yong, et al.
Publicado: (2023)

Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS
por: Hellbach, Fabian, et al.
Publicado: (2022)

Higher dietary protein intake is associated with sarcopenia in older British twins
por: Ni Lochlainn, Mary, et al.
Publicado: (2023)

Association of FTO gene variants with body composition in UK twins
por: Livshits, Gregory, et al.
Publicado: (2012)

An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health
por: Verdi, Serena, et al.
Publicado: (2018)

Dietary Protein and Muscle in Aging People: The Potential Role of the Gut Microbiome
por: Ni Lochlainn, Mary, et al.
Publicado: (2018)

Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study
por: Livshits, Gregory, et al.
Publicado: (2011)

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort
por: Nag, Abhishek, et al.
Publicado: (2014)

An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker
por: Livshits, Gregory, et al.
Publicado: (2015)

The composition of the gut microbiome differs among community dwelling older people with good and poor appetite
por: Cox, Natalie J., et al.
Publicado: (2021)

Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain
por: Livshits, Gregory, et al.
Publicado: (2017)

The Association between Chronic Widespread Musculoskeletal Pain, Depression and Fatigue Is Genetically Mediated
por: Burri, Andrea, et al.
Publicado: (2015)

Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank
por: Cherny, Stacey S., et al.
Publicado: (2020)

Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine Study
por: Livshits, Gregory, et al.
Publicado: (2010)

The relationship between naevus count, memory function and telomere length in the Twins UK cohort
por: Masi, Stefano, et al.
Publicado: (2018)

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins
por: Livshits, Gregory, et al.
Publicado: (2016)

Neuropathic pain as part of chronic widespread pain: environmental and genetic influences
por: Momi, Sukhleen K., et al.
Publicado: (2015)

Understanding the complex genetic architecture connecting rheumatoid arthritis, osteoporosis and inflammation: discovering causal pathways
por: Kasher, Melody, et al.
Publicado: (2022)

Are Epigenetic Factors Implicated in Chronic Widespread Pain?
por: Burri, Andrea, et al.
Publicado: (2016)

Metabolomic markers of fatigue: Association between circulating metabolome and fatigue in women with chronic widespread pain
por: Freidin, Maxim B., et al.
Publicado: (2018)

Gut microbiota associations with common diseases and prescription medications in a population-based cohort
por: Jackson, Matthew A., et al.
Publicado: (2018)

Epigenetic findings in periodontitis in UK twins: a cross-sectional study
por: Kurushima, Yuko, et al.
Publicado: (2019)

Characterisation, procedures and heritability of acute dietary intake in the Twins UK cohort: an observational study
por: Leeming, Emily R., et al.
Publicado: (2022)

Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins
por: Mesnage, Robin, et al.
Publicado: (2022)

Signatures of early frailty in the gut microbiota
por: Jackson, Matt, et al.
Publicado: (2016)

From the Data on Many, Precision Medicine for “One”: The Case for Widespread Genomic Data Sharing
por: Scollen, Serena, et al.
Publicado: (2017)

Widespread smell testing for COVID-19 has limited application – Authors' reply
por: Menni, Cristina, et al.
Publicado: (2020)

Chronic widespread pain is associated with worsening frailty in European men
por: Wade, Katie Fredrika, et al.
Publicado: (2016)

Nutrition and Frailty: Opportunities for Prevention and Treatment
por: Ni Lochlainn, Mary, et al.
Publicado: (2021)

Increased habitual flavonoid intake predicts attenuation of cognitive ageing in twins
por: Jennings, Amy, et al.
Publicado: (2021)

Erratum to: signatures of early frailty in the gut microbiota
por: Jackson, Matthew A., et al.
Publicado: (2016)

Widespread gaps in the quality of care for primary biliary cholangitis in UK
por: Sivakumar, Mathuri, et al.
Publicado: (2021)

K-means for shared frailty models
por: Govindarajulu, Usha, et al.
Publicado: (2022)

Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?
por: Bai, Ge, et al.
Publicado: (2021)

PPI‐Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort
por: Zhang, Xinyuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q7pr553oje77tpvo97vt7lkgcu