Estimating error models for whole genome sequencing using mixtures of Dirichlet-multinomial distributions

MOTIVATION: Accurate identification of genotypes is an essential part of the analysis of genomic data, including in identification of sequence polymorphisms, linking mutations with disease and determining mutation rates. Biological and technical processes that adversely affect genotyping include cop...

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Detalles Bibliográficos
Autores principales: Wu, Steven H, Schwartz, Rachel S, Winter, David J, Conrad, Donald F, Cartwright, Reed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860108/
https://www.ncbi.nlm.nih.gov/pubmed/28334373
http://dx.doi.org/10.1093/bioinformatics/btx133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860108/
https://www.ncbi.nlm.nih.gov/pubmed/28334373
http://dx.doi.org/10.1093/bioinformatics/btx133

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