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Estimating error models for whole genome sequencing using mixtures of Dirichlet-multinomial distributions
MOTIVATION: Accurate identification of genotypes is an essential part of the analysis of genomic data, including in identification of sequence polymorphisms, linking mutations with disease and determining mutation rates. Biological and technical processes that adversely affect genotyping include cop...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860108/ https://www.ncbi.nlm.nih.gov/pubmed/28334373 http://dx.doi.org/10.1093/bioinformatics/btx133 |