The neXtProt peptide uniqueness checker: a tool for the proteomics community

SUMMARY: The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid var...

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Detalles Bibliográficos
Autores principales: Schaeffer, Mathieu, Gateau, Alain, Teixeira, Daniel, Michel, Pierre-André, Zahn-Zabal, Monique, Lane, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860159/
https://www.ncbi.nlm.nih.gov/pubmed/28520855
http://dx.doi.org/10.1093/bioinformatics/btx318
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author Schaeffer, Mathieu
Gateau, Alain
Teixeira, Daniel
Michel, Pierre-André
Zahn-Zabal, Monique
Lane, Lydie
author_facet Schaeffer, Mathieu
Gateau, Alain
Teixeira, Daniel
Michel, Pierre-André
Zahn-Zabal, Monique
Lane, Lydie
author_sort Schaeffer, Mathieu
collection PubMed
description SUMMARY: The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid variants. AVAILABILITY AND IMPLEMENTATION: The pepx program is available at https://github.com/calipho-sib/pepx and can be launched from the command line or through a cgi web interface. Indexing requires a sequence file in FASTA format. The peptide uniqueness checker tool is freely available on the web at https://www.nextprot.org/tools/peptide-uniqueness-checker and from the neXtProt API at https://api.nextprot.org/.
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spelling pubmed-58601592018-03-21 The neXtProt peptide uniqueness checker: a tool for the proteomics community Schaeffer, Mathieu Gateau, Alain Teixeira, Daniel Michel, Pierre-André Zahn-Zabal, Monique Lane, Lydie Bioinformatics Applications Notes SUMMARY: The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid variants. AVAILABILITY AND IMPLEMENTATION: The pepx program is available at https://github.com/calipho-sib/pepx and can be launched from the command line or through a cgi web interface. Indexing requires a sequence file in FASTA format. The peptide uniqueness checker tool is freely available on the web at https://www.nextprot.org/tools/peptide-uniqueness-checker and from the neXtProt API at https://api.nextprot.org/. Oxford University Press 2017-11-01 2017-05-17 /pmc/articles/PMC5860159/ /pubmed/28520855 http://dx.doi.org/10.1093/bioinformatics/btx318 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Schaeffer, Mathieu
Gateau, Alain
Teixeira, Daniel
Michel, Pierre-André
Zahn-Zabal, Monique
Lane, Lydie
The neXtProt peptide uniqueness checker: a tool for the proteomics community
title The neXtProt peptide uniqueness checker: a tool for the proteomics community
title_full The neXtProt peptide uniqueness checker: a tool for the proteomics community
title_fullStr The neXtProt peptide uniqueness checker: a tool for the proteomics community
title_full_unstemmed The neXtProt peptide uniqueness checker: a tool for the proteomics community
title_short The neXtProt peptide uniqueness checker: a tool for the proteomics community
title_sort nextprot peptide uniqueness checker: a tool for the proteomics community
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860159/
https://www.ncbi.nlm.nih.gov/pubmed/28520855
http://dx.doi.org/10.1093/bioinformatics/btx318
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