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LinkageMapView—rendering high-resolution linkage and QTL maps

MOTIVATION: Linkage and quantitative trait loci (QTL) maps are critical tools for the study of the genetic basis of complex traits. With the advances in sequencing technology over the past decade, linkage map densities have been increasing dramatically, while the visualization tools have not kept pa...

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Detalles Bibliográficos
Autores principales: Ouellette, Lisa A, Reid, Robert W, Blanchard, Steven G, Brouwer, Cory R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860205/
https://www.ncbi.nlm.nih.gov/pubmed/28968706
http://dx.doi.org/10.1093/bioinformatics/btx576
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author Ouellette, Lisa A
Reid, Robert W
Blanchard, Steven G
Brouwer, Cory R
author_facet Ouellette, Lisa A
Reid, Robert W
Blanchard, Steven G
Brouwer, Cory R
author_sort Ouellette, Lisa A
collection PubMed
description MOTIVATION: Linkage and quantitative trait loci (QTL) maps are critical tools for the study of the genetic basis of complex traits. With the advances in sequencing technology over the past decade, linkage map densities have been increasing dramatically, while the visualization tools have not kept pace. LinkageMapView is a free add-on package written in R that produces high resolution, publication-ready visualizations of linkage and QTL maps. While there is software available to generate linkage map graphics, none are freely available, produce publication quality figures, are open source and can run on all platforms. LinkageMapView can be integrated into map building pipelines as it seamlessly incorporates output from R/qtl and also accepts simple text or comma delimited files. There are numerous options within the package to build highly customizable maps, allow for linkage group comparisons, and annotate QTL regions. AVAILABILITY AND IMPLEMENTATION: https://cran.r-project.org/web/packages/LinkageMapView/
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spelling pubmed-58602052018-03-21 LinkageMapView—rendering high-resolution linkage and QTL maps Ouellette, Lisa A Reid, Robert W Blanchard, Steven G Brouwer, Cory R Bioinformatics Applications Notes MOTIVATION: Linkage and quantitative trait loci (QTL) maps are critical tools for the study of the genetic basis of complex traits. With the advances in sequencing technology over the past decade, linkage map densities have been increasing dramatically, while the visualization tools have not kept pace. LinkageMapView is a free add-on package written in R that produces high resolution, publication-ready visualizations of linkage and QTL maps. While there is software available to generate linkage map graphics, none are freely available, produce publication quality figures, are open source and can run on all platforms. LinkageMapView can be integrated into map building pipelines as it seamlessly incorporates output from R/qtl and also accepts simple text or comma delimited files. There are numerous options within the package to build highly customizable maps, allow for linkage group comparisons, and annotate QTL regions. AVAILABILITY AND IMPLEMENTATION: https://cran.r-project.org/web/packages/LinkageMapView/ Oxford University Press 2018-01-15 2017-09-13 /pmc/articles/PMC5860205/ /pubmed/28968706 http://dx.doi.org/10.1093/bioinformatics/btx576 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Ouellette, Lisa A
Reid, Robert W
Blanchard, Steven G
Brouwer, Cory R
LinkageMapView—rendering high-resolution linkage and QTL maps
title LinkageMapView—rendering high-resolution linkage and QTL maps
title_full LinkageMapView—rendering high-resolution linkage and QTL maps
title_fullStr LinkageMapView—rendering high-resolution linkage and QTL maps
title_full_unstemmed LinkageMapView—rendering high-resolution linkage and QTL maps
title_short LinkageMapView—rendering high-resolution linkage and QTL maps
title_sort linkagemapview—rendering high-resolution linkage and qtl maps
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860205/
https://www.ncbi.nlm.nih.gov/pubmed/28968706
http://dx.doi.org/10.1093/bioinformatics/btx576
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