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FATHMM-XF: accurate prediction of pathogenic point mutations via extended features
SUMMARY: We present FATHMM-XF, a method for predicting pathogenic point mutations in the human genome. Drawing on an extensive feature set, FATHMM-XF outperforms competitors on benchmark tests, particularly in non-coding regions where the majority of pathogenic mutations are likely to be found. AVAI...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860356/ https://www.ncbi.nlm.nih.gov/pubmed/28968714 http://dx.doi.org/10.1093/bioinformatics/btx536 |