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diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data
SUMMARY: The 3D architecture of DNA within the nucleus is a key determinant of interactions between genes, regulatory elements, and transcriptional machinery. As a result, differences in DNA looping structure are associated with variation in gene expression and cell state. To systematically assess c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860605/ https://www.ncbi.nlm.nih.gov/pubmed/29028898 http://dx.doi.org/10.1093/bioinformatics/btx623 |