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New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing

BACKGROUND: Atypical meningiomas are common central nervous system neoplasms with high recurrence rate and poorer prognosis compared to their grade I counterparts. Surgical excision and radiotherapy remains the mainstay therapy but medical treatments are limited. We explore new drug candidates using...

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Detalles Bibliográficos
Autores principales: Zador, Zsolt, King, Andrew T., Geifman, Nophar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860760/
https://www.ncbi.nlm.nih.gov/pubmed/29558515
http://dx.doi.org/10.1371/journal.pone.0194701