SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation

Glycogen synthase kinase 3 (GSK3) is a critical regulator of diverse cellular functions involved in the maintenance of structure and function. Enzymatic activity of GSK3 is inhibited by N-terminal serine phosphorylation. However, alternate post-translational mechanism(s) responsible for GSK3 inactiv...

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Detalles Bibliográficos
Autores principales: Sarikhani, Mohsen, Mishra, Sneha, Maity, Sangeeta, Kotyada, Chaithanya, Wolfgeher, Donald, Gupta, Mahesh P, Singh, Mahavir, Sundaresan, Nagalingam R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860870/
https://www.ncbi.nlm.nih.gov/pubmed/29504933
http://dx.doi.org/10.7554/eLife.32952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860870/
https://www.ncbi.nlm.nih.gov/pubmed/29504933
http://dx.doi.org/10.7554/eLife.32952

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