Exposure to human alveolar lining fluid enhances Mycobacterium bovis BCG vaccine efficacy against Mycobacterium tuberculosis infection in a CD8+ T cell dependent manner

Current tuberculosis (TB) treatments include chemotherapy and preventative vaccination with Mycobacterium bovis Bacillus Calmette-Guérin (BCG). In humans, however, BCG vaccination fails to fully protect against pulmonary TB. Few studies have considered the impact of the human lung mucosa [alveolar l...

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Detalles Bibliográficos
Autores principales: Moliva, Juan I., Hossfeld, Austin P., Canan, Cynthia H., Dwivedi, Varun, Wewers, Mark D., Beamer, Gillian, Turner, Joanne, Torrelles, Jordi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860920/
https://www.ncbi.nlm.nih.gov/pubmed/28930287
http://dx.doi.org/10.1038/mi.2017.80

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