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Late cornified envelope 1C (LCE1C), a transcriptional target of TAp63 phosphorylated at T46/T281, interacts with PRMT5

p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 phosphorylated at T46/T281 specifically upregulates the late...

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Detalles Bibliográficos
Autores principales: Yabuta, Norikazu, Ota, Chie, Sasakura, Towa, Naito, Yoko, Okuzaki, Daisuke, Fukushima, Kohshiro, Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861035/
https://www.ncbi.nlm.nih.gov/pubmed/29559659
http://dx.doi.org/10.1038/s41598-018-23045-7