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Intrauterine growth restriction - impact on cardiovascular diseases later in life

Intrauterine growth restriction (IUGR) is a fetal pathology which leads to increased risk for certain neonatal complications. Furthermore, clinical and experimental studies revealed that IUGR is associated with a significantly higher incidence of metabolic, renal and cardiovascular diseases (CVD) la...

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Detalles Bibliográficos
Autores principales: Menendez-Castro, Carlos, Rascher, Wolfgang, Hartner, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861253/
https://www.ncbi.nlm.nih.gov/pubmed/29560535
http://dx.doi.org/10.1186/s40348-018-0082-5
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author Menendez-Castro, Carlos
Rascher, Wolfgang
Hartner, Andrea
author_facet Menendez-Castro, Carlos
Rascher, Wolfgang
Hartner, Andrea
author_sort Menendez-Castro, Carlos
collection PubMed
description Intrauterine growth restriction (IUGR) is a fetal pathology which leads to increased risk for certain neonatal complications. Furthermore, clinical and experimental studies revealed that IUGR is associated with a significantly higher incidence of metabolic, renal and cardiovascular diseases (CVD) later in life. One hypothesis for the higher risk of CVD after IUGR postulates that IUGR induces metabolic alterations that then lead to CVD. This minireview focuses on recent studies which demonstrate that IUGR is followed by early primary cardiovascular alterations which may directly progress to CVD later in life.
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spelling pubmed-58612532018-03-23 Intrauterine growth restriction - impact on cardiovascular diseases later in life Menendez-Castro, Carlos Rascher, Wolfgang Hartner, Andrea Mol Cell Pediatr Mini Review Intrauterine growth restriction (IUGR) is a fetal pathology which leads to increased risk for certain neonatal complications. Furthermore, clinical and experimental studies revealed that IUGR is associated with a significantly higher incidence of metabolic, renal and cardiovascular diseases (CVD) later in life. One hypothesis for the higher risk of CVD after IUGR postulates that IUGR induces metabolic alterations that then lead to CVD. This minireview focuses on recent studies which demonstrate that IUGR is followed by early primary cardiovascular alterations which may directly progress to CVD later in life. Springer Berlin Heidelberg 2018-03-20 /pmc/articles/PMC5861253/ /pubmed/29560535 http://dx.doi.org/10.1186/s40348-018-0082-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Mini Review
Menendez-Castro, Carlos
Rascher, Wolfgang
Hartner, Andrea
Intrauterine growth restriction - impact on cardiovascular diseases later in life
title Intrauterine growth restriction - impact on cardiovascular diseases later in life
title_full Intrauterine growth restriction - impact on cardiovascular diseases later in life
title_fullStr Intrauterine growth restriction - impact on cardiovascular diseases later in life
title_full_unstemmed Intrauterine growth restriction - impact on cardiovascular diseases later in life
title_short Intrauterine growth restriction - impact on cardiovascular diseases later in life
title_sort intrauterine growth restriction - impact on cardiovascular diseases later in life
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861253/
https://www.ncbi.nlm.nih.gov/pubmed/29560535
http://dx.doi.org/10.1186/s40348-018-0082-5
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