Computational prediction of drug solubility in water-based systems: Qualitative and quantitative approaches used in the current drug discovery and development setting

In this review we will discuss recent advances in computational prediction of solubility in water-based solvents. Our focus is set on recent advances in predictions of biorelevant solubility in media mimicking the human intestinal fluids and on new methods to predict the thermodynamic cycle rather t...

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Detalles Bibliográficos
Autores principales: Bergström, Christel A.S., Larsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861307/
https://www.ncbi.nlm.nih.gov/pubmed/29421301
http://dx.doi.org/10.1016/j.ijpharm.2018.01.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861307/
https://www.ncbi.nlm.nih.gov/pubmed/29421301
http://dx.doi.org/10.1016/j.ijpharm.2018.01.044

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