Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase

The piggyBac transposase (PB) is distinguished by its activity and utility in genome engineering, especially in humans where it has highly promising therapeutic potential. Little is known, however, about the structure–function relationships of the different domains of PB. Here, we demonstrate in vit...

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Detalles Bibliográficos
Autores principales: Morellet, Nelly, Li, Xianghong, Wieninger, Silke A, Taylor, Jennifer L, Bischerour, Julien, Moriau, Séverine, Lescop, Ewen, Bardiaux, Benjamin, Mathy, Nathalie, Assrir, Nadine, Bétermier, Mireille, Nilges, Michael, Hickman, Alison B, Dyda, Fred, Craig, Nancy L, Guittet, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861402/
https://www.ncbi.nlm.nih.gov/pubmed/29385532
http://dx.doi.org/10.1093/nar/gky044

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