Cargando…
RecA requires two molecules of Mg(2+) ions for its optimal strand exchange activity in vitro
Mg(2+) ion stimulates the DNA strand exchange reaction catalyzed by RecA, a key step in homologous recombination. To elucidate the molecular mechanisms underlying the role of Mg(2+) and the strand exchange reaction itself, we investigated the interaction of RecA with Mg(2+) and sought to determine w...
Autores principales: | Kim, Raeyeong, Kanamaru, Shuji, Mikawa, Tsutomu, Prévost, Chantal, Ishii, Kentaro, Ito, Kentaro, Uchiyama, Susumu, Oda, Masayuki, Iwasaki, Hiroshi, Kim, Seog K, Takahashi, Masayuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861410/ https://www.ncbi.nlm.nih.gov/pubmed/29390145 http://dx.doi.org/10.1093/nar/gky048 |
Ejemplares similares
-
Nonfilament-forming RecA dimer catalyzes homologous joint formation
por: Shinohara, Takeshi, et al.
Publicado: (2018) -
Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments
por: Conover, Alyson J., et al.
Publicado: (2011) -
Complementary strand relocation may play vital roles in RecA-based homology recognition
por: Peacock-Villada, Alexandra, et al.
Publicado: (2012) -
RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange
por: Bonde, Nina J, et al.
Publicado: (2022) -
Single-molecule studies of the stringency factors and rates governing the polymerization of RecA on double-stranded DNA
por: Feinstein, Efraim, et al.
Publicado: (2011)