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Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics

Short read massive parallel sequencing has emerged as a standard diagnostic tool in the medical setting. However, short read technologies have inherent limitations such as GC bias, difficulties mapping to repetitive elements, trouble discriminating paralogous sequences, and difficulties in phasing a...

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Detalles Bibliográficos
Autores principales: Ardui, Simon, Ameur, Adam, Vermeesch, Joris R, Hestand, Matthew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861413/
https://www.ncbi.nlm.nih.gov/pubmed/29401301
http://dx.doi.org/10.1093/nar/gky066

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