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THiCweed: fast, sensitive detection of sequence features by clustering big datasets

We present THiCweed, a new approach to analyzing transcription factor binding data from high-throughput chromatin immunoprecipitation-sequencing (ChIP-seq) experiments. THiCweed clusters bound regions based on sequence similarity using a divisive hierarchical clustering approach based on sequence si...

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Detalles Bibliográficos
Autores principales: Agrawal, Ankit, Sambare, Snehal V, Narlikar, Leelavati, Siddharthan, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861420/
https://www.ncbi.nlm.nih.gov/pubmed/29267972
http://dx.doi.org/10.1093/nar/gkx1251