APE2 promotes DNA damage response pathway from a single-strand break

As the most common type of DNA damage, DNA single-strand breaks (SSBs) are primarily repaired by the SSB repair mechanism. If not repaired properly or promptly, unrepaired SSBs lead to genome stability and have been implicated in cancer and neurodegenerative diseases. However, it remains unknown how...

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Detalles Bibliográficos
Autores principales: Lin, Yunfeng, Bai, Liping, Cupello, Steven, Hossain, Md Akram, Deem, Bradley, McLeod, Melissa, Raj, Jude, Yan, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861430/
https://www.ncbi.nlm.nih.gov/pubmed/29361157
http://dx.doi.org/10.1093/nar/gky020

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