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Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements

In single stranded (+)-sense RNA viruses, RNA structural elements (SEs) play essential roles in the infection process from replication to encapsidation. Using selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq) and covariation analysis, we explore the structural featu...

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Detalles Bibliográficos
Autores principales: Watters, Kyle E, Choudhary, Krishna, Aviran, Sharon, Lucks, Julius B, Perry, Keith L, Thompson, Jeremy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861449/
https://www.ncbi.nlm.nih.gov/pubmed/29294088
http://dx.doi.org/10.1093/nar/gkx1273