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In silico drug combination discovery for personalized cancer therapy

BACKGROUND: Drug combination therapy, which is considered as an alternative to single drug therapy, can potentially reduce resistance and toxicity, and have synergistic efficacy. As drug combination therapies are widely used in the clinic for hypertension, asthma, and AIDS, they have also been propo...

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Detalles Bibliográficos
Autores principales: Jeon, Minji, Kim, Sunkyu, Park, Sungjoon, Lee, Heewon, Kang, Jaewoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861486/
https://www.ncbi.nlm.nih.gov/pubmed/29560824
http://dx.doi.org/10.1186/s12918-018-0546-1