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Improving the measurement of semantic similarity by combining gene ontology and co-functional network: a random walk based approach

BACKGROUND: Gene Ontology (GO) is one of the most popular bioinformatics resources. In the past decade, Gene Ontology-based gene semantic similarity has been effectively used to model gene-to-gene interactions in multiple research areas. However, most existing semantic similarity approaches rely onl...

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Detalles Bibliográficos
Autores principales: Peng, Jiajie, Zhang, Xuanshuo, Hui, Weiwei, Lu, Junya, Li, Qianqian, Liu, Shuhui, Shang, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861498/
https://www.ncbi.nlm.nih.gov/pubmed/29560823
http://dx.doi.org/10.1186/s12918-018-0539-0

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