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Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

BACKGROUND: Apolipoprotein E (ApoE) is the major carrier protein that mediates the transport and delivery of cholesterol and other lipids in the brain. Three isoforms of ApoE (ApoE2, ApoE3, ApoE4) exist in humans, and their relative expression levels impact HIV-1 infection, HIV-1/AIDS disease progre...

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Detalles Bibliográficos
Autores principales:	Khan, Nabab, Datta, Gaurav, Geiger, Jonathan D., Chen, Xuesong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861635/ https://www.ncbi.nlm.nih.gov/pubmed/29558961 http://dx.doi.org/10.1186/s12974-018-1129-1

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