IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes

BACKGROUND: Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations? METHODS: Five hundred twenty eight patients were recruited in a prospective observational multicentre cohort (PROMISE) s...

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Detalles Bibliográficos
Autores principales: Egli, Adrian, Mandal, Jyotshna, Schumann, Desiree M., Roth, Michael, Thomas, Brad, Lorne Tyrrell, D., Blasi, Francesco, Kostikas, Kostantinos, Boersma, Wim, Milenkovic, Branislava, Lacoma, Alicia, Rentsch, Katharina, Rohde, Gernot G. U., Louis, Renaud, Aerts, Joachim G., Welte, Tobias, Torres, Antoni, Tamm, Michael, Stolz, Daiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861655/
https://www.ncbi.nlm.nih.gov/pubmed/29562888
http://dx.doi.org/10.1186/s12890-018-0616-6

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