Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse model

BACKGROUND: Early pulmonary oxygen exposure is one of the most important factors implicated in the development of bronchopulmonary dysplasia (BPD). METHODS: Here, we analyzed short- and long-term effects of neonatal hyperoxia on NOS3 and STAT3 expression and corresponding epigenetic signatures using...

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Detalles Bibliográficos
Autores principales: Chao, Cho-Ming, van den Bruck, Rhea, Lork, Samantha, Merkle, Janica, Krampen, Laura, Weil, Patrick P, Aydin, Malik, Bellusci, Saverio, Jenke, Andreas C., Postberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861728/
https://www.ncbi.nlm.nih.gov/pubmed/29581793
http://dx.doi.org/10.1186/s13148-018-0469-0

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