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Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China
OBJECTIVES: We aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults. METHODS: We performed a prospective cohort study in 150 391 hypertensive participants aged...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862003/ https://www.ncbi.nlm.nih.gov/pubmed/29120959 http://dx.doi.org/10.1097/HJH.0000000000001601 |
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author | Fan, Mengyu Yu, Canqing Guo, Yu Bian, Zheng Li, Xia Yang, Ling Chen, Yiping Li, Mingqiang Li, Xianzhi Chen, Junshi Chen, Zhengming Lv, Jun Li, Liming |
author_facet | Fan, Mengyu Yu, Canqing Guo, Yu Bian, Zheng Li, Xia Yang, Ling Chen, Yiping Li, Mingqiang Li, Xianzhi Chen, Junshi Chen, Zhengming Lv, Jun Li, Liming |
author_sort | Fan, Mengyu |
collection | PubMed |
description | OBJECTIVES: We aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults. METHODS: We performed a prospective cohort study in 150 391 hypertensive participants aged 30–79 years from the China Kadoorie Biobank study of 512 891 participants recruited from 10 diverse areas across China during 2004–2008. Participants with heart disease, stroke, chronic obstructive pulmonary disease, and cancer at baseline were excluded. RESULTS: During 1069 863 person-years of follow-up (median 7.1 years), a total of 5332 men and 4384 women died. Compared with hypertensive participants in the lowest level of total physical activity, the hazard ratios for all-cause mortality were 0.80 (0.76–0.84), 0.69 (0.65–0.73), and 0.67 (0.62–0.72) for those in quartiles 2–4 (P(trend) < 0.001), respectively. Inverse associations were also observed for cardiovascular mortality. Being active in occupational, domestic, and leisure time were associated with lower risk of all-cause and cardiovascular mortality. However, the adjusted ratio for active commuting was 1.08 (1.02–1.15) for all-cause mortality. High levels of low-intensity, moderate-intensity, and vigorous-intensity physical activity were consistently associated with lower risks of all-cause and cardiovascular mortality. CONCLUSION: Among Chinese hypertensive adults, a higher level of physical activity reduces all-cause and cardiovascular mortality, independent of intensities of physical activity. Not only leisure-time but also occupational and domestic physical activities were benefited. |
format | Online Article Text |
id | pubmed-5862003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-58620032018-03-28 Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China Fan, Mengyu Yu, Canqing Guo, Yu Bian, Zheng Li, Xia Yang, Ling Chen, Yiping Li, Mingqiang Li, Xianzhi Chen, Junshi Chen, Zhengming Lv, Jun Li, Liming J Hypertens ORIGINAL PAPERS: Lifestyle OBJECTIVES: We aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults. METHODS: We performed a prospective cohort study in 150 391 hypertensive participants aged 30–79 years from the China Kadoorie Biobank study of 512 891 participants recruited from 10 diverse areas across China during 2004–2008. Participants with heart disease, stroke, chronic obstructive pulmonary disease, and cancer at baseline were excluded. RESULTS: During 1069 863 person-years of follow-up (median 7.1 years), a total of 5332 men and 4384 women died. Compared with hypertensive participants in the lowest level of total physical activity, the hazard ratios for all-cause mortality were 0.80 (0.76–0.84), 0.69 (0.65–0.73), and 0.67 (0.62–0.72) for those in quartiles 2–4 (P(trend) < 0.001), respectively. Inverse associations were also observed for cardiovascular mortality. Being active in occupational, domestic, and leisure time were associated with lower risk of all-cause and cardiovascular mortality. However, the adjusted ratio for active commuting was 1.08 (1.02–1.15) for all-cause mortality. High levels of low-intensity, moderate-intensity, and vigorous-intensity physical activity were consistently associated with lower risks of all-cause and cardiovascular mortality. CONCLUSION: Among Chinese hypertensive adults, a higher level of physical activity reduces all-cause and cardiovascular mortality, independent of intensities of physical activity. Not only leisure-time but also occupational and domestic physical activities were benefited. Lippincott Williams & Wilkins 2018-04 2017-11-08 /pmc/articles/PMC5862003/ /pubmed/29120959 http://dx.doi.org/10.1097/HJH.0000000000001601 Text en Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | ORIGINAL PAPERS: Lifestyle Fan, Mengyu Yu, Canqing Guo, Yu Bian, Zheng Li, Xia Yang, Ling Chen, Yiping Li, Mingqiang Li, Xianzhi Chen, Junshi Chen, Zhengming Lv, Jun Li, Liming Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title | Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title_full | Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title_fullStr | Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title_full_unstemmed | Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title_short | Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China |
title_sort | effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in china |
topic | ORIGINAL PAPERS: Lifestyle |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862003/ https://www.ncbi.nlm.nih.gov/pubmed/29120959 http://dx.doi.org/10.1097/HJH.0000000000001601 |
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