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Inhibition of ERK1/2 or AKT Activity Equally Enhances Radiation Sensitization in B16F10 Cells

BACKGROUND: The aim of the study was to evaluate the radiation sensitizing ability of ERK1/2, PI3K-AKT and JNK inhibitors in highly radiation resistant and metastatic B16F10 cells which carry wild-type Ras and Braf. METHODS: Mouse melanoma cell line B16F10 was exposed to 1.0, 2.0 and 3.0 Gy of elect...

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Detalles Bibliográficos
Autores principales:	Kalal, Bhuvanesh Sukhlal, Fathima, Faraz, Pai, Vinitha Ramanath, Sanjeev, Ganesh, Krishna, Chilakapati Murali, Upadhya, Dinesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elmer Press 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862079/ https://www.ncbi.nlm.nih.gov/pubmed/29581812 http://dx.doi.org/10.14740/wjon1088w

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