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A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature

The incidence of tonsillar cancer has increased by four times in the United States over the last few decades likely due to recent increase in human papilloma virus (HPV) infections. The stage of the tumor predicts likelihood of metastasis, with advanced stages associated with higher chances of metas...

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Autores principales: Tariq, Hassan, Kamal, Muhammad Umar, Mehershahi, Shehriyar, Saad, Muhammad, Azam, Sara, Kumar, Kishore, Niazi, Masooma, Makker, Jasbir, Daniel, Myrta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862081/
https://www.ncbi.nlm.nih.gov/pubmed/29581814
http://dx.doi.org/10.14740/wjon1073w
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author Tariq, Hassan
Kamal, Muhammad Umar
Mehershahi, Shehriyar
Saad, Muhammad
Azam, Sara
Kumar, Kishore
Niazi, Masooma
Makker, Jasbir
Daniel, Myrta
author_facet Tariq, Hassan
Kamal, Muhammad Umar
Mehershahi, Shehriyar
Saad, Muhammad
Azam, Sara
Kumar, Kishore
Niazi, Masooma
Makker, Jasbir
Daniel, Myrta
author_sort Tariq, Hassan
collection PubMed
description The incidence of tonsillar cancer has increased by four times in the United States over the last few decades likely due to recent increase in human papilloma virus (HPV) infections. The stage of the tumor predicts likelihood of metastasis, with advanced stages associated with higher chances of metastasis. The squamous cell carcinomas (SCCs) of the head and neck commonly metastasize to the lung, bone and liver in descending order. Tonsillar cancer rarely involves the small bowel and our review of the literature did not reveal any reported case of metastasis to the colon/large bowel. Our patient had locally metastatic tonsillar cancer, treated with partial pharyngectomy and selective neck dissection but later developed several bone and colonic metastases concurrently, likely secondary to hematogeneous dissemination after a few months of therapy. To the best of our knowledge, large bowel metastasis from head and neck SCC has never been reported in the literature. In these patients presenting with atypical gastrointestinal symptoms, a high index of suspicion should be maintained to determine the extent of metastasis and identify other metastatic sites.
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spelling pubmed-58620812018-03-26 A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature Tariq, Hassan Kamal, Muhammad Umar Mehershahi, Shehriyar Saad, Muhammad Azam, Sara Kumar, Kishore Niazi, Masooma Makker, Jasbir Daniel, Myrta World J Oncol Case Report The incidence of tonsillar cancer has increased by four times in the United States over the last few decades likely due to recent increase in human papilloma virus (HPV) infections. The stage of the tumor predicts likelihood of metastasis, with advanced stages associated with higher chances of metastasis. The squamous cell carcinomas (SCCs) of the head and neck commonly metastasize to the lung, bone and liver in descending order. Tonsillar cancer rarely involves the small bowel and our review of the literature did not reveal any reported case of metastasis to the colon/large bowel. Our patient had locally metastatic tonsillar cancer, treated with partial pharyngectomy and selective neck dissection but later developed several bone and colonic metastases concurrently, likely secondary to hematogeneous dissemination after a few months of therapy. To the best of our knowledge, large bowel metastasis from head and neck SCC has never been reported in the literature. In these patients presenting with atypical gastrointestinal symptoms, a high index of suspicion should be maintained to determine the extent of metastasis and identify other metastatic sites. Elmer Press 2018-02 2018-03-08 /pmc/articles/PMC5862081/ /pubmed/29581814 http://dx.doi.org/10.14740/wjon1073w Text en Copyright 2018, Tariq et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tariq, Hassan
Kamal, Muhammad Umar
Mehershahi, Shehriyar
Saad, Muhammad
Azam, Sara
Kumar, Kishore
Niazi, Masooma
Makker, Jasbir
Daniel, Myrta
A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title_full A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title_fullStr A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title_full_unstemmed A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title_short A Rare Case of Colonic Metastases From Tonsillar Carcinoma: Case Report and Review of Literature
title_sort rare case of colonic metastases from tonsillar carcinoma: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862081/
https://www.ncbi.nlm.nih.gov/pubmed/29581814
http://dx.doi.org/10.14740/wjon1073w
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